Sophie Gobeil-en

Sophie Gobeil, Département de biochimie, microbiologie et bio-informatique


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Institut de biologie Intégrative et des systèmes

Pavillon Charles-Eugène Marchand

418 656-2131 # 409137


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I am an assistant professor in the Department of Biochemistry, Microbiology and Bioinformatics of the Faculty of Science and Engineering at Université Laval. I am affiliated with the Institute of Integrative Biology and Systems (IBIS) and a member of PROTEO (The Quebec Network for Research on Protein Function, Engineering, and Applications; and the Université Laval Infectious Disease Research Center ( As a biochemist and structural biologist, I am interested in the role of proteins’ conformational dynamics (i.e. motions) towards their function, evolution, and in the formation of protein-protein interactions.

Current research projects within my group investigate the role of proteins structural dynamics in: (1) promoting immune evasion, (2) formation of antigen-antibody interface and this, for protein engineering and therapeutics design applications, and (3) in host-pathogen interactions. Our approach relies on an integrative structural biology pipeline combining X-ray crystallography, cryogenic electron microscopy (cryo-EM), and nuclear magnetic resonance (NMR) methodologies, coupled with biochemical and biophysical protein characterization assays.

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